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Urinary myeloid IgA Fc alpha receptor (CD89) and transglutaminase-2 as new biomarkers for active IgA nephropathy and henoch-Schönlein purpura nephritis

BACKGROUND: IgA nephropathy (IgAN) and Henoch-Schönlein purpura nephritis (HSPN) are glomerular diseases that share a common and central pathogenic mechanism. The formation of immune complexes containing IgA1, myeloid IgA Fc alpha receptor (FcαRI/CD89) and transglutaminase-2 (TG2) is observed in bot...

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Detalles Bibliográficos
Autores principales: Moresco, Rafael N., Speeckaert, Marijn M., Zmonarski, Slawomir C., Krajewska, Magdalena, Komuda-Leszek, Ewa, Perkowska-Ptasinska, Agnieszka, Gesualdo, Loreto, Rocchetti, Maria T., Delanghe, Sigurd E., Vanholder, Raymond, Van Biesen, Wim, Delanghe, Joris R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802400/
https://www.ncbi.nlm.nih.gov/pubmed/27051593
http://dx.doi.org/10.1016/j.bbacli.2016.02.002