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A Dynamical Framework for the All-or-None G1/S Transition

The transition from G1 into DNA replication (S phase) is an emergent behavior resulting from dynamic and complex interactions between cyclin-dependent kinases (Cdks), Cdk inhibitors (CKIs), and the anaphase-promoting complex/cyclosome (APC/C). Understanding the cellular decision to commit to S phase...

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Detalles Bibliográficos
Autores principales:	Barr, Alexis R., Heldt, Frank S., Zhang, Tongli, Bakal, Chris, Novák, Béla
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802413/ https://www.ncbi.nlm.nih.gov/pubmed/27136687 http://dx.doi.org/10.1016/j.cels.2016.01.001

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