Integrated Transcriptome and Proteome Analyses Reveal Organ-Specific Proteome Deterioration in Old Rats

Aging is associated with the decline of protein, cell, and organ function. Here, we use an integrated approach to characterize gene expression, bulk translation, and cell biology in the brains and livers of young and old rats. We identify 468 differences in protein abundance between young and old an...

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Detalles Bibliográficos
Autores principales: Ori, Alessandro, Toyama, Brandon H., Harris, Michael S., Bock, Thomas, Iskar, Murat, Bork, Peer, Ingolia, Nicholas T., Hetzer, Martin W., Beck, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802414/
https://www.ncbi.nlm.nih.gov/pubmed/27135913
http://dx.doi.org/10.1016/j.cels.2015.08.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802414/
https://www.ncbi.nlm.nih.gov/pubmed/27135913
http://dx.doi.org/10.1016/j.cels.2015.08.012

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