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Trimethylamine N‐Oxide Promotes Vascular Inflammation Through Signaling of Mitogen‐Activated Protein Kinase and Nuclear Factor‐κB
BACKGROUND: The choline‐derived metabolite trimethylamine N‐oxide (TMAO) has been demonstrated to contribute to atherosclerosis and is associated with coronary artery disease risk. METHODS AND RESULTS: We explored the impact of TMAO on endothelial and smooth muscle cell function in vivo, focusing on...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802459/ https://www.ncbi.nlm.nih.gov/pubmed/26903003 http://dx.doi.org/10.1161/JAHA.115.002767 |