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Tetrahydrobiopterin Supplementation Improves Endothelial Function But Does Not Alter Aortic Stiffness in Patients With Rheumatoid Arthritis

BACKGROUND: Rheumatoid arthritis is a systemic inflammatory condition associated with increased cardiovascular risk that may be due to underlying endothelial dysfunction and subsequent aortic stiffening. We hypothesized that supplementation with tetrahydrobiopterin (BH (4)) would recouple endothelia...

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Detalles Bibliográficos
Autores principales: Mäki‐Petäjä, Kaisa M., Day, Lisa, Cheriyan, Joseph, Hall, Frances C., Östör, Andrew J. K., Shenker, Nicholas, Wilkinson, Ian B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802470/
https://www.ncbi.nlm.nih.gov/pubmed/26896473
http://dx.doi.org/10.1161/JAHA.115.002762