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β3 Adrenergic Stimulation Restores Nitric Oxide/Redox Balance and Enhances Endothelial Function in Hyperglycemia

BACKGROUND: Perturbed balance between NO and O(2) (•−). (ie, NO/redox imbalance) is central in the pathobiology of diabetes‐induced vascular dysfunction. We examined whether stimulation of β(3) adrenergic receptors (β(3) ARs), coupled to endothelial nitric oxide synthase (eNOS) activation, would re‐...

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Detalles Bibliográficos
Autores principales: Karimi Galougahi, Keyvan, Liu, Chia‐Chi, Garcia, Alvaro, Gentile, Carmine, Fry, Natasha A., Hamilton, Elisha J., Hawkins, Clare L., Figtree, Gemma A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802476/
https://www.ncbi.nlm.nih.gov/pubmed/26896479
http://dx.doi.org/10.1161/JAHA.115.002824