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Allogeneic Mesenchymal Stromal Cells Transplanted Onto the Heart Surface Achieve Therapeutic Myocardial Repair Despite Immunologic Responses in Rats

BACKGROUND: Transplantation of allogeneic mesenchymal stromal cells (MSCs) is a promising treatment for heart failure. We have shown that epicardial placement of cell sheets markedly increases donor cell survival and augments therapeutic effects compared with the current methods. Although immune rej...

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Detalles Bibliográficos
Autores principales: Tano, Nobuko, Kaneko, Masahiro, Ichihara, Yuki, Ikebe, Chiho, Coppen, Steven R., Shiraishi, Manabu, Shintani, Yasunori, Yashiro, Kenta, Warrens, Anthony, Suzuki, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802488/
https://www.ncbi.nlm.nih.gov/pubmed/26896478
http://dx.doi.org/10.1161/JAHA.115.002815