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Modeling the integration of bacterial rRNA fragments into the human cancer genome

BACKGROUND: Cancer is a disease driven by the accumulation of genomic alterations, including the integration of exogenous DNA into the human somatic genome. We previously identified in silico evidence of DNA fragments from a Pseudomonas-like bacteria integrating into the 5′-UTR of four proto-oncogen...

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Detalles Bibliográficos
Autores principales: Sieber, Karsten B., Gajer, Pawel, Dunning Hotopp, Julie C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802584/
https://www.ncbi.nlm.nih.gov/pubmed/27001685
http://dx.doi.org/10.1186/s12859-016-0982-0