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Modeling the integration of bacterial rRNA fragments into the human cancer genome
BACKGROUND: Cancer is a disease driven by the accumulation of genomic alterations, including the integration of exogenous DNA into the human somatic genome. We previously identified in silico evidence of DNA fragments from a Pseudomonas-like bacteria integrating into the 5′-UTR of four proto-oncogen...
Autores principales: | Sieber, Karsten B., Gajer, Pawel, Dunning Hotopp, Julie C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802584/ https://www.ncbi.nlm.nih.gov/pubmed/27001685 http://dx.doi.org/10.1186/s12859-016-0982-0 |
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