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Retinoic acid receptor signaling preserves tendon stem cell characteristics and prevents spontaneous differentiation in vitrox

BACKGROUND: Previous studies have reported that adult mesenchymal stem cells (MSCs) tend to gradually lose their stem cell characteristics in vitro when placed outside their niche environment. They subsequently undergo spontaneous differentiation towards mesenchymal lineages after only a few passage...

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Detalles Bibliográficos
Autores principales: Webb, Stuart, Gabrelow, Chase, Pierce, James, Gibb, Edwin, Elliott, Jimmy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802591/
https://www.ncbi.nlm.nih.gov/pubmed/27001426
http://dx.doi.org/10.1186/s13287-016-0306-3