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Retinoic acid receptor signaling preserves tendon stem cell characteristics and prevents spontaneous differentiation in vitrox
BACKGROUND: Previous studies have reported that adult mesenchymal stem cells (MSCs) tend to gradually lose their stem cell characteristics in vitro when placed outside their niche environment. They subsequently undergo spontaneous differentiation towards mesenchymal lineages after only a few passage...
Autores principales: | Webb, Stuart, Gabrelow, Chase, Pierce, James, Gibb, Edwin, Elliott, Jimmy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802591/ https://www.ncbi.nlm.nih.gov/pubmed/27001426 http://dx.doi.org/10.1186/s13287-016-0306-3 |
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