Leveraging protein quaternary structure to identify oncogenic driver mutations

BACKGROUND: Identifying key “driver” mutations which are responsible for tumorigenesis is critical in the development of new oncology drugs. Due to multiple pharmacological successes in treating cancers that are caused by such driver mutations, a large body of methods have been developed to differen...

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Detalles Bibliográficos
Autores principales: Ryslik, Gregory A., Cheng, Yuwei, Modis, Yorgo, Zhao, Hongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802602/
https://www.ncbi.nlm.nih.gov/pubmed/27001666
http://dx.doi.org/10.1186/s12859-016-0963-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802602/
https://www.ncbi.nlm.nih.gov/pubmed/27001666
http://dx.doi.org/10.1186/s12859-016-0963-3

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