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Leveraging protein quaternary structure to identify oncogenic driver mutations
BACKGROUND: Identifying key “driver” mutations which are responsible for tumorigenesis is critical in the development of new oncology drugs. Due to multiple pharmacological successes in treating cancers that are caused by such driver mutations, a large body of methods have been developed to differen...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802602/ https://www.ncbi.nlm.nih.gov/pubmed/27001666 http://dx.doi.org/10.1186/s12859-016-0963-3 |