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Common molecular mechanism of the hepatic lesion and the cardiac parasympathetic regulation in chronic hepatitis C infection: a critical role for the muscarinic receptor type 3

BACKGROUND: The pathophysiological overlapping between Sjorgen’s Syndrome (SS) and HCV, presence of anti- muscarinic receptor type 3 (M3R) antibodies in SS, the role that M3R plays in the regulation of the heart rate, has led to the assumption that cardiovagal dysfunction in HCV patients is caused b...

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Detalles Bibliográficos
Autores principales: Glišić, Sanja, Cavanaugh, David P., Chittur, Krishnan K., Sencanski, Milan, Perovic, Vladimir, Bojić, Tijana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802633/
https://www.ncbi.nlm.nih.gov/pubmed/27000565
http://dx.doi.org/10.1186/s12859-016-0988-7