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CTCF regulates NELF, DSIF and P-TEFb recruitment during transcription

CTCF is a versatile transcription factor with well-established roles in chromatin organization and insulator function. Recent findings also implicate CTCF in the control of elongation by RNA polymerase (RNAP) II. Here we show that CTCF knockdown abrogates RNAP II pausing at the early elongation chec...

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Detalles Bibliográficos
Autores principales: Laitem, Clélia, Zaborowska, Justyna, Tellier, Michael, Yamaguchi, Yuki, Cao, Qingfu, Egloff, Sylvain, Handa, Hiroshi, Murphy, Shona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802788/
https://www.ncbi.nlm.nih.gov/pubmed/26399478
http://dx.doi.org/10.1080/21541264.2015.1095269