BRCA testing, treatment patterns and survival in platinum-sensitive recurrent ovarian cancer – an observational cohort study

BACKGROUND: Breast cancer associated (BRCA) genes are critical for DNA repair. Mutations in BRCA1 and BRCA2 (BRCAm) result in loss of these repair mechanisms and potential carcinogenesis. Germline BRCAm are common in ovarian carcinomas, particularly in platinum-sensitive disease. The increased preva...

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Detalles Bibliográficos
Autores principales: Unni, Sudhir K., Schauerhamer, Marisa B., Deka, Rishi, Tyczynski, Jerzy E., Fernandes, Ancilla W., Stevens, Vanessa, Brixner, Diana I., Stenehjem, David D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802840/
https://www.ncbi.nlm.nih.gov/pubmed/27004793
http://dx.doi.org/10.1186/s13048-016-0227-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802840/
https://www.ncbi.nlm.nih.gov/pubmed/27004793
http://dx.doi.org/10.1186/s13048-016-0227-x

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