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COX-2 modulates mammary tumor progression in response to collagen density
BACKGROUND: High breast density is linked to an increased risk of breast cancer, and correlates with changes in collagen. In a mouse model of mammary carcinoma in the context of increased collagen deposition, the MMTV-PyMT/Col1a1(tm1jae), there is accelerated mammary tumor formation and progression....
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802888/ https://www.ncbi.nlm.nih.gov/pubmed/27000374 http://dx.doi.org/10.1186/s13058-016-0695-3 |