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COX-2 modulates mammary tumor progression in response to collagen density

BACKGROUND: High breast density is linked to an increased risk of breast cancer, and correlates with changes in collagen. In a mouse model of mammary carcinoma in the context of increased collagen deposition, the MMTV-PyMT/Col1a1(tm1jae), there is accelerated mammary tumor formation and progression....

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Detalles Bibliográficos
Autores principales:	Esbona, Karla, Inman, David, Saha, Sandeep, Jeffery, Justin, Schedin, Pepper, Wilke, Lee, Keely, Patricia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802888/ https://www.ncbi.nlm.nih.gov/pubmed/27000374 http://dx.doi.org/10.1186/s13058-016-0695-3

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