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Intestinal CCL25 expression is increased in colitis and correlates with inflammatory activity

CCL25-mediated activation of CCR9 is critical for mucosal lymphocyte recruitment to the intestine. In immune-mediated liver injury complicating inflammatory bowel disease, intrahepatic activation of this pathway allows mucosal lymphocytes to be recruited to the liver, driving hepatobiliary destructi...

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Detalles Bibliográficos
Autores principales: Trivedi, Palak J., Bruns, Tony, Ward, Stephen, Mai, Martina, Schmidt, Carsten, Hirschfield, Gideon M., Weston, Chris J., Adams, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803021/
https://www.ncbi.nlm.nih.gov/pubmed/26873648
http://dx.doi.org/10.1016/j.jaut.2016.01.001