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Building up the nucleus: nuclear organization in the establishment of totipotency and pluripotency during mammalian development
In mammals, epigenetic reprogramming, the acquisition and loss of totipotency, and the first cell fate decision all occur within a 3-d window after fertilization from the one-cell zygote to the formation of the blastocyst. These processes are poorly understood in molecular detail, yet this is an ess...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803048/ https://www.ncbi.nlm.nih.gov/pubmed/26980186 http://dx.doi.org/10.1101/gad.273805.115 |