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A decade of the anaphase-promoting complex in the nervous system

Control of protein abundance by the ubiquitin–proteasome system is essential for normal brain development and function. Just over a decade ago, the first post-mitotic function of the anaphase-promoting complex, a major cell cycle-regulated E3 ubiquitin ligase, was discovered in the control of axon g...

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Detalles Bibliográficos
Autores principales: Huang, Ju, Bonni, Azad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803049/
https://www.ncbi.nlm.nih.gov/pubmed/26980187
http://dx.doi.org/10.1101/gad.274324.115