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Mte1 interacts with Mph1 and promotes crossover recombination and telomere maintenance

Mph1 is a member of the conserved FANCM family of DNA motor proteins that play key roles in genome maintenance processes underlying Fanconi anemia, a cancer predisposition syndrome in humans. Here, we identify Mte1 as a novel interactor of the Mph1 helicase in Saccharomyces cerevisiae. In vitro, Mte...

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Detalles Bibliográficos
Autores principales: Silva, Sonia, Altmannova, Veronika, Luke-Glaser, Sarah, Henriksen, Peter, Gallina, Irene, Yang, Xuejiao, Choudhary, Chunaram, Luke, Brian, Krejci, Lumir, Lisby, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803055/
https://www.ncbi.nlm.nih.gov/pubmed/26966248
http://dx.doi.org/10.1101/gad.276204.115