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Mte1 interacts with Mph1 and promotes crossover recombination and telomere maintenance
Mph1 is a member of the conserved FANCM family of DNA motor proteins that play key roles in genome maintenance processes underlying Fanconi anemia, a cancer predisposition syndrome in humans. Here, we identify Mte1 as a novel interactor of the Mph1 helicase in Saccharomyces cerevisiae. In vitro, Mte...
Autores principales: | Silva, Sonia, Altmannova, Veronika, Luke-Glaser, Sarah, Henriksen, Peter, Gallina, Irene, Yang, Xuejiao, Choudhary, Chunaram, Luke, Brian, Krejci, Lumir, Lisby, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803055/ https://www.ncbi.nlm.nih.gov/pubmed/26966248 http://dx.doi.org/10.1101/gad.276204.115 |
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