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Poly(ADP-Ribose) Glycohydrolase (PARG) Silencing Suppresses Benzo(a)pyrene Induced Cell Transformation

Benzo(a)pyrene (BaP) is a ubiquitously distributed environmental pollutant and known carcinogen, which can induce malignant transformation in rodent and human cells. Poly(ADP-ribose) glycohydrolase (PARG), the primary enzyme that catalyzes the degradation of poly(ADP-ribose) (PAR), has been known to...

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Detalles Bibliográficos
Autores principales: Li, Xuan, Li, Xiyi, Zhu, Zhiliang, Huang, Peiwu, Zhuang, Zhixiong, Liu, Jianjun, Gao, Wei, Liu, Yinpin, Huang, Haiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803271/
https://www.ncbi.nlm.nih.gov/pubmed/27003318
http://dx.doi.org/10.1371/journal.pone.0151172