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Poly(ADP-Ribose) Glycohydrolase (PARG) Silencing Suppresses Benzo(a)pyrene Induced Cell Transformation
Benzo(a)pyrene (BaP) is a ubiquitously distributed environmental pollutant and known carcinogen, which can induce malignant transformation in rodent and human cells. Poly(ADP-ribose) glycohydrolase (PARG), the primary enzyme that catalyzes the degradation of poly(ADP-ribose) (PAR), has been known to...
Autores principales: | Li, Xuan, Li, Xiyi, Zhu, Zhiliang, Huang, Peiwu, Zhuang, Zhixiong, Liu, Jianjun, Gao, Wei, Liu, Yinpin, Huang, Haiyan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803271/ https://www.ncbi.nlm.nih.gov/pubmed/27003318 http://dx.doi.org/10.1371/journal.pone.0151172 |
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