The glucose metabolite methylglyoxal inhibits expression of the glucose transporter genes by inactivating the cell surface glucose sensors Rgt2 and Snf3 in yeast

Methylglyoxal (MG) is a cytotoxic by-product of glycolysis. MG has inhibitory effect on the growth of cells ranging from microorganisms to higher eukaryotes, but its molecular targets are largely unknown. The yeast cell-surface glucose sensors Rgt2 and Snf3 function as glucose receptors that sense e...

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Detalles Bibliográficos
Autores principales: Roy, Adhiraj, Hashmi, Salman, Li, Zerui, Dement, Angela D., Hong Cho, Kyu, Kim, Jeong-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803311/
https://www.ncbi.nlm.nih.gov/pubmed/26764094
http://dx.doi.org/10.1091/mbc.E15-11-0789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803311/
https://www.ncbi.nlm.nih.gov/pubmed/26764094
http://dx.doi.org/10.1091/mbc.E15-11-0789

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