Multimodal MRI Evaluation of the MitoPark Mouse Model of Parkinson’s Disease

The MitoPark mouse, a relatively new genetic model of Parkinson’s disease (PD), has a dopaminergic neuron-specific knock-out that inactivates the mitochondrial transcription factor A (Tfam), a protein essential for mitochondrial DNA expression and maintenance. This study used multimodal MRI to chara...

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Detalles Bibliográficos
Autores principales: Cong, Linlin, Muir, Eric R., Chen, Cang, Qian, Yusheng, Liu, Jingwei, Biju, K. C., Clark, Robert A., Li, Senlin, Duong, Timothy Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803323/
https://www.ncbi.nlm.nih.gov/pubmed/27003179
http://dx.doi.org/10.1371/journal.pone.0151884

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803323/
https://www.ncbi.nlm.nih.gov/pubmed/27003179
http://dx.doi.org/10.1371/journal.pone.0151884

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