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Multimodal MRI Evaluation of the MitoPark Mouse Model of Parkinson’s Disease
The MitoPark mouse, a relatively new genetic model of Parkinson’s disease (PD), has a dopaminergic neuron-specific knock-out that inactivates the mitochondrial transcription factor A (Tfam), a protein essential for mitochondrial DNA expression and maintenance. This study used multimodal MRI to chara...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803323/ https://www.ncbi.nlm.nih.gov/pubmed/27003179 http://dx.doi.org/10.1371/journal.pone.0151884 |