TLR4-Dependent Secretion by Hepatic Stellate Cells of the Neutrophil-Chemoattractant CXCL1 Mediates Liver Response to Gut Microbiota

BACKGROUND & AIMS: The gut microbiota significantly influences hepatic immunity. Little is known on the precise mechanism by which liver cells mediate recognition of gut microbes at steady state. Here we tested the hypothesis that a specific liver cell population was the sensor and we aimed at d...

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Detalles Bibliográficos
Autores principales: Bigorgne, Amélie E., John, Beena, Ebrahimkhani, Mohammad R., Shimizu-Albergine, Masami, Campbell, Jean S., Crispe, Ian N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803332/
https://www.ncbi.nlm.nih.gov/pubmed/27002851
http://dx.doi.org/10.1371/journal.pone.0151063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803332/
https://www.ncbi.nlm.nih.gov/pubmed/27002851
http://dx.doi.org/10.1371/journal.pone.0151063

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