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KMAD: knowledge-based multiple sequence alignment for intrinsically disordered proteins

Summary: Intrinsically disordered proteins (IDPs) lack tertiary structure and thus differ from globular proteins in terms of their sequence–structure–function relations. IDPs have lower sequence conservation, different types of active sites and a different distribution of functionally important regi...

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Detalles Bibliográficos
Autores principales: Lange, Joanna, Wyrwicz, Lucjan S., Vriend, Gert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803389/
https://www.ncbi.nlm.nih.gov/pubmed/26568635
http://dx.doi.org/10.1093/bioinformatics/btv663