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miR-20a regulates expression of the iron exporter ferroportin in lung cancer

ABSTRACT: Ferroportin (FPN) exports iron from duodenal enterocytes, macrophages, and hepatocytes to maintain systemic iron homeostasis. In addition, FPN is expressed in various cancer cells. Here, we show that in lung cancer, FPN expression is regulated by miR-20a. Within the FPN-3′-untranslated reg...

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Detalles Bibliográficos
Autores principales: Babu, Kamesh R., Muckenthaler, Martina U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803811/
https://www.ncbi.nlm.nih.gov/pubmed/26560875
http://dx.doi.org/10.1007/s00109-015-1362-3