A Regulatory Feedback between Plasmacytoid Dendritic Cells and Regulatory B Cells Is Aberrant in Systemic Lupus Erythematosus

Signals controlling the generation of regulatory B (Breg) cells remain ill-defined. Here we report an “auto”-regulatory feedback mechanism between plasmacytoid dendritic cells (pDCs) and Breg cells. In healthy individuals, pDCs drive the differentiation of CD19(+)CD24(hi)CD38(hi) (immature) B cells...

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Detalles Bibliográficos
Autores principales: Menon, Madhvi, Blair, Paul A., Isenberg, David A., Mauri, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803914/
https://www.ncbi.nlm.nih.gov/pubmed/26968426
http://dx.doi.org/10.1016/j.immuni.2016.02.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803914/
https://www.ncbi.nlm.nih.gov/pubmed/26968426
http://dx.doi.org/10.1016/j.immuni.2016.02.012

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