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Effect of Blocking of Neuropeptide Y Y2 Receptor on Tumor Angiogenesis and Progression in Normal and Diet-Induced Obese C57BL/6 Mice

BACKGROUND: Obesity is a risk factor for some types of cancers. Angiogenesis is a necessary step in the multistage progression of tumors such as melanoma. Previous studies reported that neuropeptide Y (NPY) regulates angiogenesis by activating the Y2 receptor on endothelial cells. The present study...

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Detalles Bibliográficos
Autores principales: Alasvand, Masoud, Rashidi, Bahman, Javanmard, S. H., Akhavan, Maziar Mohammad, Khazaei, Majid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Canadian Center of Science and Education 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803968/
https://www.ncbi.nlm.nih.gov/pubmed/26153206
http://dx.doi.org/10.5539/gjhs.v7n7p69