MicroRNA-378 limits activation of hepatic stellate cells and liver fibrosis by suppressing Gli3 expression

Hedgehog (Hh) signalling regulates hepatic fibrogenesis. MicroRNAs (miRNAs) mediate various cellular processes; however, their role in liver fibrosis is unclear. Here we investigate regulation of miRNAs in chronically damaged fibrotic liver. MiRNA profiling shows that expression of miR-378 family me...

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Detalles Bibliográficos
Autores principales: Hyun, Jeongeun, Wang, Sihyung, Kim, Jieun, Rao, Kummara Madhusudana, Park, Soo Yong, Chung, Ildoo, Ha, Chang-Sik, Kim, Sang-Woo, Yun, Yang H., Jung, Youngmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804167/
https://www.ncbi.nlm.nih.gov/pubmed/27001906
http://dx.doi.org/10.1038/ncomms10993

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804167/
https://www.ncbi.nlm.nih.gov/pubmed/27001906
http://dx.doi.org/10.1038/ncomms10993

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