Mondo complexes regulate TFEB via TOR inhibition to promote longevity in response to gonadal signals

Germline removal provokes longevity in several species and shifts resources towards survival and repair. Several Caenorhabditis elegans transcription factors regulate longevity arising from germline removal; yet, how they work together is unknown. Here we identify a Myc-like HLH transcription factor...

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Detalles Bibliográficos
Autores principales: Nakamura, Shuhei, Karalay, Özlem, Jäger, Philipp S., Horikawa, Makoto, Klein, Corinna, Nakamura, Kayo, Latza, Christian, Templer, Sven E., Dieterich, Christoph, Antebi, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804169/
https://www.ncbi.nlm.nih.gov/pubmed/27001890
http://dx.doi.org/10.1038/ncomms10944

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804169/
https://www.ncbi.nlm.nih.gov/pubmed/27001890
http://dx.doi.org/10.1038/ncomms10944

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