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TFIIS.h, a new target of p53, regulates transcription efficiency of pro-apoptotic bax gene

Tumor suppressor p53 transcriptionally regulates hundreds of genes involved in various cellular functions. However, the detailed mechanisms underlying the selection of p53 targets in response to different stresses are still elusive. Here, we identify TFIIS.h, a transcription elongation factor, as a...

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Detalles Bibliográficos
Autores principales: Liao, Jun-Ming, Cao, Bo, Deng, Jun, Zhou, Xiang, Strong, Michael, Zeng, Shelya, Xiong, Jianping, Flemington, Erik, Lu, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804275/
https://www.ncbi.nlm.nih.gov/pubmed/27005522
http://dx.doi.org/10.1038/srep23542