Gastrointestinal safety, chemotherapeutic potential, and classic pharmacological profile of NOSH‐naproxen (AVT‐219) a dual NO‐ and H(2)S‐releasing hybrid

Naproxen (NAP) is a potent nonsteroidal anti‐inflammatory drug (NSAID) with a favorable cardiovascular profile. However, its long‐term use may lead to serious gastrointestinal and renal side effects. NOSH‐ (nitric oxide and hydrogen sulfide) releasing naproxen (NOSH‐NAP, AVT‐219) belongs to a new cl...

Descripción completa

Detalles Bibliográficos
Autores principales: Chattopadhyay, Mitali, Kodela, Ravinder, Duvalsaint, Pascale L., Kashfi, Khosrow
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804313/
https://www.ncbi.nlm.nih.gov/pubmed/27069635
http://dx.doi.org/10.1002/prp2.224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804313/
https://www.ncbi.nlm.nih.gov/pubmed/27069635
http://dx.doi.org/10.1002/prp2.224

Ejemplares similares