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Downregulation of the Ca(2+)‐activated K(+) channel K(C) (a)3.1 by histone deacetylase inhibition in human breast cancer cells

The intermediate‐conductance Ca(2+)‐activated K(+) channel K(C) (a)3.1 is involved in the promotion of tumor growth and metastasis, and is a potential therapeutic target and biomarker for cancer. Histone deacetylase inhibitors (HDACis) have considerable potential for cancer therapy, however, the eff...

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Detalles Bibliográficos
Autores principales: Ohya, Susumu, Kanatsuka, Saki, Hatano, Noriyuki, Kito, Hiroaki, Matsui, Azusa, Fujimoto, Mayu, Matsuba, Sayo, Niwa, Satomi, Zhan, Peng, Suzuki, Takayoshi, Muraki, Katsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804315/
https://www.ncbi.nlm.nih.gov/pubmed/27069638
http://dx.doi.org/10.1002/prp2.228