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Deguelin‐induced blockade of PI3K/protein kinase B/MAP kinase signaling in zebrafish and breast cancer cell lines is mediated by down‐regulation of fibroblast growth factor receptor 4 activity

Deguelin, a natural component derived from leguminous plants, has been used as pesticide in some regions. Accumulating evidence show that deguelin has promising chemopreventive and therapeutic activities against cancer cells. This study shows that low concentrations of deguelin can lead to significa...

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Detalles Bibliográficos
Autores principales: Wu, Wei, Hai, Yang, Chen, Lu, Liu, Rui‐Jin, Han, Yu‐Xiang, Li, Wen‐Hao, Li, Song, Lin, Shuo, Wu, Xin‐Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804323/
https://www.ncbi.nlm.nih.gov/pubmed/27069628
http://dx.doi.org/10.1002/prp2.212