Cargando…
Mechanisms of the gabapentinoids and α (2) δ‐1 calcium channel subunit in neuropathic pain
The gabapentinoid drugs gabapentin and pregabalin are key front‐line therapies for various neuropathies of peripheral and central origin. Originally designed as analogs of GABA, the gabapentinoids bind to the α (2) δ‐1 and α (2) δ‐2 auxiliary subunits of calcium channels, though only the former has...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804325/ https://www.ncbi.nlm.nih.gov/pubmed/27069626 http://dx.doi.org/10.1002/prp2.205 |