Iron depletion suppresses mTORC1-directed signalling in intestinal Caco-2 cells via induction of REDD1

Iron is an indispensable micronutrient that regulates many aspects of cell function, including growth and proliferation. These processes are critically dependent upon signalling via the mammalian or mechanistic target of rapamycin complex 1 (mTORC1). Herein, we test whether iron depletion induced by...

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Detalles Bibliográficos
Autores principales: Watson, Ailsa, Lipina, Christopher, McArdle, Harry J., Taylor, Peter M., Hundal, Harinder S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804389/
https://www.ncbi.nlm.nih.gov/pubmed/26827808
http://dx.doi.org/10.1016/j.cellsig.2016.01.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804389/
https://www.ncbi.nlm.nih.gov/pubmed/26827808
http://dx.doi.org/10.1016/j.cellsig.2016.01.014

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