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Iron depletion suppresses mTORC1-directed signalling in intestinal Caco-2 cells via induction of REDD1
Iron is an indispensable micronutrient that regulates many aspects of cell function, including growth and proliferation. These processes are critically dependent upon signalling via the mammalian or mechanistic target of rapamycin complex 1 (mTORC1). Herein, we test whether iron depletion induced by...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Science Ltd
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804389/ https://www.ncbi.nlm.nih.gov/pubmed/26827808 http://dx.doi.org/10.1016/j.cellsig.2016.01.014 |