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Failure to Identify Somatic Mutations in Monozygotic Twins Discordant for Schizophrenia by Whole Exome Sequencing

BACKGROUND: Schizophrenia (SCZ) is a severe, debilitating, and complex psychiatric disorder with multiple causative factors. An increasing number of studies have determined that rare variations play an important role in its etiology. A somatic mutation is a rare form of genetic variation that occurs...

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Detalles Bibliográficos
Autores principales: Lyu, Nan, Guan, Li-Li, Ma, Hong, Wang, Xi-Jin, Wu, Bao-Ming, Shang, Fan-Hong, Wang, Dan, Wen, Hong, Yu, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804415/
https://www.ncbi.nlm.nih.gov/pubmed/26960372
http://dx.doi.org/10.4103/0366-6999.178009