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Active centromere and chromosome identification in fixed cell lines
BACKGROUND: The centromere plays a crucial role in ensuring the fidelity of chromosome segregation during cell divisions. However, in cancer and constitutional disorders, the presence of more than one active centromere on a chromosome may be a contributing factor to chromosome instability and could...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804480/ https://www.ncbi.nlm.nih.gov/pubmed/27011768 http://dx.doi.org/10.1186/s13039-016-0236-x |