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Novel point mutations in the ERG11 gene in clinical isolates of azole resistant Candida species

The azoles are the class of medications most commonly used to fight infections caused by Candida sp. Typically, resistance can be attributed to mutations in ERG11 gene (CYP51) which encodes the cytochrome P450 14α-demethylase, the primary target for the activity of azoles. The objective of this stud...

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Detalles Bibliográficos
Autores principales: Silva, Danielly Beraldo dos Santos, Rodrigues, Luana Mireli Carbonera, de Almeida, Adriana Araújo, de Oliveira, Kelly Mari Pires, Grisolia/, Alexéia Barufatti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804502/
https://www.ncbi.nlm.nih.gov/pubmed/26982177
http://dx.doi.org/10.1590/0074-02760150400