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Pharmacokinetic and pharmacodynamic responses in adult patients with Chagas disease treated with a new formulation of benznidazole

Pharmacological treatment of Chagas disease with benznidazole (BNZ) is effective in children in all stages, but it is controversial in chronically infected adults. We report the pharmacokinetics and pharmacodynamics in six adult patients with Chagas disease treated with the new BNZ formulation (ABAR...

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Detalles Bibliográficos
Autores principales: Fernández, Marisa Liliana, Marson, Maria Elena, Ramirez, Juan Carlos, Mastrantonio, Guido, Schijman, Alejandro Gabriel, Altcheh, Jaime, Riarte, Adelina Rosa, Bournissen, Facundo García
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804505/
https://www.ncbi.nlm.nih.gov/pubmed/26982179
http://dx.doi.org/10.1590/0074-02760150401