CTCF-mediated chromatin loops enclose inducible gene regulatory domains

BACKGROUND: The CCTC-binding factor (CTCF) protein is involved in genome organization, including mediating three-dimensional chromatin interactions. Human patient lymphocytes with mutations in a single copy of the CTCF gene have reduced expression of enhancer-associated genes involved in response to...

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Detalles Bibliográficos
Autores principales: Oti, Martin, Falck, Jonas, Huynen, Martijn A., Zhou, Huiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804521/
https://www.ncbi.nlm.nih.gov/pubmed/27004515
http://dx.doi.org/10.1186/s12864-016-2516-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804521/
https://www.ncbi.nlm.nih.gov/pubmed/27004515
http://dx.doi.org/10.1186/s12864-016-2516-6

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