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Long noncoding RNAs expressed in human hepatic stellate cells form networks with extracellular matrix proteins

BACKGROUND: Hepatic fibrosis is the underlying cause of cirrhosis and liver failure in nearly every form of chronic liver disease, and hepatic stellate cells (HSCs) are the primary cell type responsible for fibrosis. Long noncoding RNAs (lncRNAs) are increasingly recognized as regulators of developm...

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Detalles Bibliográficos
Autores principales: Zhou, Chan, York, Samuel R., Chen, Jennifer Y., Pondick, Joshua V., Motola, Daniel L., Chung, Raymond T., Mullen, Alan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804564/
https://www.ncbi.nlm.nih.gov/pubmed/27007663
http://dx.doi.org/10.1186/s13073-016-0285-0