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Induction of α-synuclein aggregate formation by CSF exosomes from patients with Parkinson’s disease and dementia with Lewy bodies

Extracellular α-synuclein has been proposed as a crucial mechanism for induction of pathological aggregate formation in previously healthy cells. In vitro, extracellular α-synuclein is partially associated with exosomal vesicles. Recently, we have provided evidence that exosomal α-synuclein is prese...

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Detalles Bibliográficos
Autores principales: Stuendl, Anne, Kunadt, Marcel, Kruse, Niels, Bartels, Claudia, Moebius, Wiebke, Danzer, Karin M., Mollenhauer, Brit, Schneider, Anja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805087/
https://www.ncbi.nlm.nih.gov/pubmed/26647156
http://dx.doi.org/10.1093/brain/awv346