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Collagen metabolic disorder induced by oxidative stress in human uterosacral ligament-derived fibroblasts: A possible pathophysiological mechanism in pelvic organ prolapse

Pelvic organ prolapse (POP) is a global health problem, for which the pathophysiological mechanism remains to be fully elucidated. The loss of extracellular matrix protein has been considered to be the most important molecular basis facilitating the development of POP. Oxidative stress (OS) is a wel...

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Detalles Bibliográficos
Autores principales: LIU, CHENG, YANG, QING, FANG, GUI, LI, BING-SHU, WU, DE-BIN, GUO, WEN-JUN, HONG, SHA-SHA, HONG, LI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805094/
https://www.ncbi.nlm.nih.gov/pubmed/26936098
http://dx.doi.org/10.3892/mmr.2016.4919